phosphatidyl-myo-inositol dimannoside synthase EC#: 2.4.1.346; ChemWhat Code: 1377687
| Product Name | phosphatidyl-myo-inositol dimannoside synthase |
| Example Structure |  |
| Synonyms | GDP-mannose-dependent monoacylated alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase, guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase, mannoslytransferase PimB’, mannosyltransferase PimB, mannosyltransferase PimB’, MgtA, MSMEG_4253, NCgl2106, PimB, pimB’, Rv0557, Rv2188c |
| EC Number | 2.4.1.346 |
| CAS Registry Number | |
| Comments | Requires Mg2+. The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs). |
| Cofactor | Mg2+ |
| History | |
| Reactions | (1) GDP-alpha-D-mannose + 2-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo- inositol = Gdp + 2,6-di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo- inositol. (2) GDP-alpha-D-mannose + 2-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl- 1D-myo-inositol = Gdp + 2-O-(6-O-acyl-alpha-D-mannosyl)-6-O-alpha-D- mannosyl-1-phosphatidyl-1D-myo-inositol. |
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