phosphatidylcholine 12-monooxygenase EC#: 1.14.18.4; ChemWhat Code: 1375752
| Product Name | phosphatidylcholine 12-monooxygenase |
| Example Structure |  |
| Synonyms | castor DELTA12-hydroxylase, CFAH12, CFAH12 protein, CpFAH, CpFAH12, DELTA12 oleate hydroxylase, FAH, FAH12, LFAH12, oleate 12-hydroxylase, oleate DELTA12-hydroxylase, oleate hydroxylase, oleoyl-12-hydroxylase, oxygenase, oleate DELTA12-mono, ricinoleic acid synthase |
| EC Number | 1.14.18.4 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from the plant Ricinus communis (castor bean), is involved in production of the 12-hydroxylated fatty acid ricinoleate. The enzyme, which shares sequence similarity with fatty-acyl desaturases, requires a cytochrome b5 as the electron donor. Formerly EC 1.14.13.26. |
| Cofactor | |
| History | |
| Reactions | A 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + 2 ferrocytochrome b5 + O(2) + 2 H(+) = a 1-acyl-2-((12R)-12-hydroxyoleoyl)-sn-glycero-3- phosphocholine + 2 ferricytochrome b5 + H(2)O. |
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