phosphatidylcholine-sterol O-acyltransferase EC#: 2.3.1.43; ChemWhat Code: 1376800
| Product Name | phosphatidylcholine-sterol O-acyltransferase |
| Example Structure | ![]() |
| Synonyms | acyltransferase, lecithin-cholesterol, cholesterol transacyltransferase, LAT, LCAT, lecithin cholesterol acyltransferase, lecithin-cholesterol acyl transferase, lecithin-cholesterol acyltransferase, lecithin/cholesterol acyltransferase, lecithin: cholesterol acyltransferase, lecithin:cholesterol acyltransferase, lysolecithin acyltransferase, phospholipid-cholesterol acyltransferase, plasma lecithin-cholesterol acyltransferase, TgLCAT |
| EC Number | 2.3.1.43 |
| CAS Registry Number | 9031-14-5 |
| Comments | Palmitoyl, oleoyl and linoleoyl residues can be transferred; a number of sterols, including cholesterol, can act as acceptors. The bacterial enzyme also catalyses the reactions of EC 3.1.1.4 phospholipase A2 and EC 3.1.1.5 lysophospholipase. |
| Cofactor | |
| History | |
| Reactions | Phosphatidylcholine + a sterol = 1-acylglycerophosphocholine + a sterol ester. |
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