phosphatidylinositol-4,5-bisphosphate 3-kinase EC#: 2.7.1.153; ChemWhat Code: 1378529
| Product Name | phosphatidylinositol-4,5-bisphosphate 3-kinase |
| Example Structure |  |
| Synonyms | class I phosphoinositide 3-kinase, class I PI3K, class IA phosphatidylinositol 3-kinase, CXCR2/phosphatidylinositol 3-kinase gamma, kinase (phosphorylating), phosphatidylinositol 4,5-diphosphate 3-, More, p101-PI3K, p110alpha, p110beta, p110delta, p110delta PI 3-kinase, p110gamma/p101, P120-PI3K, phosphatidyl-inositol-3-kinase, phosphatidylinositol (4,5)-bisphosphate 3-hydroxykinase, phosphatidylinositol 3′-kinase, phosphatidylinositol 3-hydroxyl kinase, phosphatidylinositol 3-kinase alpha, phosphatidylinositol 3-kinase gamma, phosphoinositide 3-kinase, phosphoinositide 3-kinase p110delta, phosphoinositol 3-kinase, PI 3-K, PI 3-kinase, PI-3K, PI3-K, PI3-kinase, PI3K, PI3K p110delta, PI3Kalpha, PI3Kbeta, PI3Kdelta, PI3Kgamma, PI3Kp110delta, PIK3CA, Pik3r1, PtdIns(4,5)P2 3-OH kinase, PtdIns-3-kinase p101, PtdIns-3-kinase p110, PtdInsP 3-OH-kinase, type I phosphoinositide 3-kinase |
| EC Number | 2.7.1.153 |
| CAS Registry Number | |
| Comments | This enzyme also catalyses the phosphorylation of PtdIns4P?to PtdIns(3,4)P2, and of PtdIns to PtdIns3P. Four mammalian isoforms are known to exist. |
| Cofactor | |
| History | |
| Reactions | Atp + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = adp + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate. |
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