| Product Name |
phosphonopyruvate hydrolase |
| Example Structure |
 |
| Synonyms |
PalA, PPH |
| EC Number |
3.11.1.3 |
| CAS Registry Number |
|
| Comments |
Highly specific for phosphonopyruvate as substrate [2]. The reaction is not inhibited by phosphate but is inhibited by the phosphonates phosphonoformic acid, hydroxymethylphosphonic acid and 3-phosphonopropanoic acid [2]. The enzyme is activated by the divalent cations Co2+, Mg2+?and Mn2+. This enzyme is a member of the phosphoenolpyruvate mutase/isocitrate lyase superfamily [3]. |
| Cofactor |
Mg2+?or?cobalt cation?or?Mn2+ |
| History |
|
| Reactions |
3-phosphonopyruvate + H(2)O = pyruvate + phosphate. |
