Product Name 
phosphoribosyl-AMP cyclohydrolase 
 
Example Structure 
 
Synonyms 
HisI, N1-(5′-phosphoribosyl) adenosine-5′-monophosphate cyclohydrolase, phosphoribosyladenosine monophosphate cyclohydrolase, PR-AMP cyclohydrolase, PRA-CH, PRAMP-cyclohydrolase 
 
EC Number 
3.5.4.19 
 
CAS Registry Number 
37289-22-8 
 
Comments 
The?Neurospora crassa?enzyme also catalyses the reactions of EC?1.1.1.23?(histidinol dehydrogenase) and EC?3.6.1.31?(phosphoribosyl-ATP diphosphatase). 
 
Cofactor 
 
History 
 
Reactions 
1-(5-phospho-beta-D-ribosyl)-AMP + H(2)O = 1-(5-phospho-beta-D-ribosyl)- 5-((5-phospho-beta-D-ribosylamino)methylideneamino)imidazole-4- carboxamide.