phosphoribosylaminoimidazole carboxylase EC#: 4.1.1.21; ChemWhat Code: 1381895
| Product Name | phosphoribosylaminoimidazole carboxylase |
| Example Structure |  |
| Synonyms | 5-Amino-1-ribosylimidazole 5-phosphate carboxylase, 5-Phosphoribosyl-5-aminoimidazole carboxylase, AdeD, AIR carboxylase, AIRC, aminoimidazole ribonucleotide carboxylase, Carboxylyase, phosphoribosylaminoimidazole, class II PurE, PAICS, phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, PurE |
| EC Number | 4.1.1.21 |
| CAS Registry Number | 9032/4/6 |
| Comments | While this is the reaction that occurs in vertebrates during purine biosynthesis, two enzymes are required to carry out the same reaction in?Escherichia coli, namely EC?6.3.4.18, 5-(carboxyamino)imidazole ribonucleotide synthase and EC?5.4.99.18, 5-(carboxyamino)imidazole ribonucleotide mutase [3]. 5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole is not a substrate. |
| Cofactor | |
| History | |
| Reactions | 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1- (5-phospho-D-ribosyl)imidazole + CO(2). |
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