phthioceranic/hydroxyphthioceranic acid synthase EC#: 2.3.1.287; ChemWhat Code: 1377124
Product Name | phthioceranic/hydroxyphthioceranic acid synthase |
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Synonyms | msl2, Pks2, polyketide synthase |
EC Number | 2.3.1.287 |
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Comments | This mycobacterial polyketide enzyme produces the hepta- and octa-methylated fatty acids known as phthioceranic acids, and presumably their hydroxylated versions. Formation of hepta- and octamethylated products depends on whether the enzyme incorporates seven or eight methylmalonyl-CoA extender units, respectively. Formation of hydroxylated products may result from the enzyme skipping the dehydratase (DH) and enoylreductase (ER) domains during the first cycle of condensation. |
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