physarolisin EC#: 3.4.21.103; ChemWhat Code: 1380641
| Product Name | physarolisin |
| Example Structure |  |
| Synonyms | EC 3.4.23.27, EC 3.4.23.6, physarolisin, physarolisin I, physarolysin II, Physarum aspartic proteinase, proteinase, Dictyostelium discoideum aspartic, proteinase, Dictyostelium discoideum aspartic, E, proteinase, Physarum flavicomum aspartic, proteinase, Physarum polycephalum acid |
| EC Number | 3.4.21.103 |
| CAS Registry Number | 94949-28-7 |
| Comments | Belongs in peptidase family?S53. From the slime mold?Physarum polycephalum. Is not inhibited by pepstatin, but is blocked by methyl 2-diazoacetamidohexanoate. Closely similar enzymes are found in?Dictyostelium discoideum?and?P. flavicomum. Formerly included in EC?3.4.23.6. |
| Cofactor | |
| History | |
| Reactions | Milk clotting activity. Preferential cleavage of 8-Gly-|-Ser-9 in B chain of insulin most rapidly, followed by 11-Leu-|-Val-12, 19-Cys(SO(3)H)-|-Gly and 24-Phe-|-Phe-25. No action on Ac-Phe-Tyr(I)(2). |
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