pikromycin synthase EC#: 1.14.15.33; ChemWhat Code: 1375724
| Product Name | pikromycin synthase |
| Example Structure |  |
| Synonyms | CYP107L1, CYP107L2, erythromycin C-12 hydroxylase, PikC |
| EC Number | 1.14.15.33 |
| CAS Registry Number | |
| Comments | A cytochrome P450 (heme-thiolate) protein. Involved in the biosynthesis of a number of bacterial macrolide antibiotics containing a desosamine glycoside unit. With narbomycin it hydroxylates at either C-12 to give pikromycin or C-14 to give neopikromycin or both positions to give narvopikromycin. With 10-deoxymethymycin it hydroxylates at either C-10 to give methymycin or C-12 to give neomethymycin or both positions to give novamethymycin. Formerly EC 1.14.13.185. |
| Cofactor | heme-thiolate |
| History | |
| Reactions |
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