plasma kallikrein EC#: 3.4.21.34; ChemWhat Code: 1380509
| Product Name | plasma kallikrein |
| Example Structure |  |
| Synonyms | bradykininogenase, callicrein, depot-Padutin, dilminal D, EC 3.4.21.8, EC 3.4.4.21, Fletcher factor, glumorin, HPK, kallidinogenase, kallikrein, kallikrein I, kallikrein II, kininogenase, kininogenin, KLK13, KLK2, KLK3, KLK4, KLK5, KLKb1, onokrein P, padreatin, padutin, pancreatic kallikrein, PK, PKal, PKKS, plasma beta-kallikrein, plasma kallikrein, plasma kallikrein¨Ckinin system, plasma KK, Plasma prekallikrein, plasma prokallikrein, porcine pancreatic kallikrein, PPK, prekallikrein, RPK, serum kallikrein, SmSP1, urinary kallikrein, urokallikrein |
| EC Number | 3.4.21.34 |
| CAS Registry Number | 9001/1/8 |
| Comments | Formed from plasma prokallikrein (Fletcher factor) by factor XIIa. Activates coagulation factors XII, VII and plasminogen. Selective for Arg > Lys in P1, in small molecule substrates. In peptidase family?S1?(trypsin family). Formerly EC?3.4.4.21?and included in EC?3.4.21.8. |
| Cofactor | |
| History | |
| Reactions | Cleaves selectively Arg-|-Xaa and Lys-|-Xaa bonds, including Lys-|-Arg and Arg-|-Ser bonds in (human) kininogen to release bradykinin. |
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