Platelet-activating factor acetyltransferase EC#: 2.3.1.149; ChemWhat Code: 1376942

Product Name Platelet-activating factor acetyltransferase
Example Structure Example Structure of Platelet-activating factor acetyltransferase EC#: 2.3.1.149
Synonyms PAF acetyltransferase, PAF-AH, PAF: acyllyso-GPC transacetylase, platelet-activating factor transacetylase
EC Number 2.3.1.149
CAS Registry Number 9012-30-0
Comments catalyses the transfer of the acetyl group from 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) to the sn-2 position of lyso-glycerophospholipids containing ethanolamine, choline, serine, inositol or phosphate groups at the sn-3 position as well as to sphingosine and long-chain fatty alcohols. The organyl group can be alkyl, acyl or alk-1-enyl (sometimes also collectively referred to as ‘radyl’).
Cofactor
History
Reactions 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso- sn-glycero-3-phospholipid = 1-organyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-acetyl-sn-glycero-3-phospholipid.

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