Involved in the biosynthesis of poly glycerol phosphate teichoic acids in bacterial cell walls. This enzyme, isolated from Bacillus subtilis 168, adds an ¦Á-D-glucose to the free OH groups of the glycerol units. The enzyme has a strong preference for UDP-¦Á-glucose as the sugar donor. It has no activity with poly(ribitol phosphate).
Cofactor
History
Reactions
n UDP-alpha-D-glucose + 4-O-(poly((2R)-glycerophospho)-(2R)- glycerophospho)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D- glucosaminyl-diphospho-ditrans,octacis-undecaprenol = n Udp + 4-O- (poly((2R)-2-alpha-D-glucosyl-1-glycerophospho)-(2R)-glycerophospho)-N- acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl- diphospho-ditrans,octacis-undecaprenol.