polyprenol reductase EC#: 1.3.1.94; ChemWhat Code: 1374064

Product Name polyprenol reductase
Example Structure Example Structure of polyprenol reductase EC#: 1.3.1.94
Synonyms DFG10, SDR5A3, SRD5A3, steroid 5alpha-reductase type 3, steroid 5alp¨¹ha-reductase type 3
EC Number 1.3.1.94
CAS Registry Number
Comments The reaction occurs in the reverse direction with reduction of the terminal double bond next to the alcohol group. Isolated from human fetal brain tissue but present in all eukaryotes. In mammalian cells dolichols are predominantly 18-21 isoprene units in length.
Cofactor
History
Reactions Ditrans,polycis-dolichol + NADP(+) = ditrans,polycis-polyprenol + Nadph.

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