PqqA peptide cyclase EC#: 1.21.98.4; ChemWhat Code: 1376096
| Product Name | PqqA peptide cyclase |
| Example Structure |  |
| Synonyms | pqqE |
| EC Number | 1.21.98.4 |
| CAS Registry Number | |
| Comments | This bacterial enzyme, which is a member of the radical SAM protein family, catalyses the formation of a C-C bond between C-4 of glutamate and C-3 of tyrosine residues of the PqqA protein (which are separated by three amino acid residues). This is the first enzymic step in the biosynthesis of the bacterial enzyme cofactor pyrroloquinoline quinone (PQQ). The reaction is dependent on the presence of flavodoxin and the accessory protein PqqD. |
| Cofactor | |
| History | |
| Reactions |
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