procollagen N-endopeptidase EC#: 3.4.24.14; ChemWhat Code: 1380961

Product Name procollagen N-endopeptidase
Example Structure Example Structure of procollagen N-endopeptidase EC#: 3.4.24.14
Synonyms ADAM-TS2, ADAMTS-2, ADAMTS14, ADAMTS2, ADAMTS3, aminoprocollagen peptidase, aminoterminal procollagen peptidase, PC I-NP, pNPI, procollagen aminopeptidase, procollagen aminoterminal protease, Procollagen I N-proteinase, Procollagen I/II amino-propeptide processing enzyme, procollagen I/II N-endopeptidase, procollagen III N-endopeptidase, procollagen III N-proteinase, Procollagen N-endopeptidase, procollagen N-protease, procollagen N-proteinase, procollagen N-terminal peptidase, procollagen N-terminal proteinase, Procollagen peptidase, type I/II procollagen N-proteinase
EC Number 3.4.24.14
CAS Registry Number 68651-94-5
Comments Removes the propeptides of type I and II collagens prior to fibril assembly. Does not act on type III collagen. In peptidase family?M12?(astacin family).
Cofactor Zn2+
History
Reactions Cleaves the N-propeptide of collagen chain alpha-1(I) at Pro-|-Gln and of alpha-1(II) and alpha-2(I) at Ala-|-Gln.

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