prolyl aminopeptidase EC#: 3.4.11.5; ChemWhat Code: 1380268

Product Name prolyl aminopeptidase
Example Structure Example Structure of prolyl aminopeptidase EC#: 3.4.11.5
Synonyms aminopeptidase P, aminopeptidase, proline, APP, cytosol aminopeptidase V, EC 3.4.1.4, L-proline aminopeptidase, L-prolyl-peptide hydrolase, More, pamA, PAP, PchPiPA, PepI, pepIP, PEPP, PIP, PiPA, Pro-X aminopeptidase, proline aminopeptidase, proline iminopeptidase, proline-specific aminopeptidase, Prolyl aminopeptidase, TePAP, Tricorn protease interacting factor F1, TsPAP1, X-pro aminopeptidase (Lactococcus)
EC Number 3.4.11.5
CAS Registry Number 9025-40-5
Comments A Mn2+-requiring enzyme present in the cytosol of mammalian and microbial cells. In contrast to the mammalian form, the bacterial form of the enzyme (type example of peptidase family S33) hydrolyses both polyproline and prolyl-2-naphthylamide. The mammalian enzyme, which is not specific for prolyl bonds, is possibly identical with EC?3.4.11.1.
Cofactor Mn2+
History
Reactions Release of N-terminal proline from a peptide.

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