propanal dehydrogenase (CoA-propanoylating) EC#: 1.2.1.87; ChemWhat Code: 1373848
| Product Name | propanal dehydrogenase (CoA-propanoylating) |
| Example Structure |  |
| Synonyms | BphJ, CoA-acylating aldehyde dehydrogenase, coenzyme A-acylating aldehyde dehydrogenase, More, PduP, TTHB247 |
| EC Number | 1.2.1.87 |
| CAS Registry Number | |
| Comments | The enzyme forms a bifunctional complex with EC 4.1.3.43, 4-hydroxy-2-oxohexanoate aldolase, with a tight channel connecting the two subunits [1,2,3]. Also acts, more slowly, on glycolaldehyde and butanal. In Pseudomonas species the enzyme forms a bifunctional complex with EC 4.1.3.39, 4-hydroxy-2-oxovalerate aldolase. The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.10, acetaldehyde dehydrogenase (acetylating). NADP+ can replace NAD+ with a much slower rate [3]. |
| Cofactor | |
| History | |
| Reactions | Propanal + CoA + NAD(+) = propanoyl-CoA + Nadh. |
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