prostaglandin-I synthase EC#: 5.3.99.4; ChemWhat Code: 1383297
| Product Name | prostaglandin-I synthase |
| Example Structure |  |
| Synonyms | Aortic cytochrom P450, CYP8A1, PGI synthase, PGI2 synthase, PGI2 synthetase, PGI2-S, PGIS, prostacyclin synthase, Prostacyclin synthetase, prostacyclin-synthase, prostacyclin/PGI2 synthase, Prostacycline synthetase, prostaglandin I synthase, Prostaglandin I2 synthase, Prostaglandin I2 synthetase, Ptgis, Synthetase, prostacyclin |
| EC Number | 5.3.99.4 |
| CAS Registry Number | |
| Comments | A cytochrome P-450 heme-thiolate enzyme. Converts prostaglandin H2?into prostaglandin I2?(prostacyclin). |
| Cofactor | heme-thiolate |
| History | |
| Reactions | (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate. |
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