prostamide/prostaglandin F2alpha synthase EC#: 1.11.1.20; ChemWhat Code: 1374852

Product Name prostamide/prostaglandin F2alpha synthase
Example Structure Example Structure of prostamide/prostaglandin F2alpha synthase EC#: 1.11.1.20
Synonyms PGF prostamide F synthase, Pmpgfs, prostaglandin F ethanolamide synthase, prostamide F synthase, prostamide/PGF synthase, prostamide/prostaglandin F synthase
EC Number 1.11.1.20
CAS Registry Number
Comments The enzyme contains a thioredoxin-type disulfide as a catalytic group. Prostamide H2 and prostaglandin H2 are the best substrates; the latter is converted to prostaglandin F2¦Á. The enzyme also reduces tert-butyl hydroperoxide, cumene hydroperoxide and H2O2, but not prostaglandin D2 or prostaglandin E2.
Cofactor
History
Reactions Thioredoxin + prostaglandin H(2) = thioredoxin disulfide + prostaglandin F(2-alpha).

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