protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase EC#: 2.4.1.313; ChemWhat Code: 1377648
| Product Name | protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase |
| Example Structure |  |
| Synonyms | B3GALNT2, beta 1,3-N-acetylgalactosaminyltransferase2, beta-1,3-N-acetylgalactosaminyltransferase 2, beta1,3-N-acetylgalactosaminyltransferase II, beta1,3-N-acetylgalactosaminyltransferase-II, beta3GalNAc-T2, UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 |
| EC Number | 2.4.1.313 |
| CAS Registry Number | |
| Comments | The human protein is specific for UDP-N-acetyl-¦Á-D-galactosamine as donor [1]. The enzyme is involved in the formation of a phosphorylated trisaccharide on a threonine residue of ¦Á-dystroglycan, an extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains. |
| Cofactor | |
| History | |
| Reactions | UDP-N-acetyl-alpha-D-galactosamine + 3-O-(N-acetyl-beta-D-glucosaminyl- (1->4)-alpha-D-mannosyl)-L-threonyl-[protein] = Udp + 3-O-(N-acetyl-beta- D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D- mannosyl)-L-threonyl-[protein]. |
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