protein O-mannose beta-1,4-N-acetylglucosaminyltransferase EC#: 2.4.1.312; ChemWhat Code: 1377647

Product Name protein O-mannose beta-1,4-N-acetylglucosaminyltransferase
Example Structure Example Structure of protein O-mannose beta-1,4-N-acetylglucosaminyltransferase EC#: 2.4.1.312
Synonyms GTDC2, O-mannose beta-1,4-N-acetylglucosaminyltransferase, POMGNT2, protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, protein O-mannose beta1,4-N-acetylglucosaminyltransferase
EC Number 2.4.1.312
CAS Registry Number
Comments The human protein is involved in the formation of a phosphorylated trisaccharide on a threonine residue of ¦Á-dystroglycan, an extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains.
Cofactor
History
Reactions UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-mannosyl)-L-threonyl- [protein] = Udp + 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D- mannosyl)-L-threonyl-[protein].I3554

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