Proteinase K EC#: 3.4.21.14 CAS#: 39450-01-6; ChemWhat Code: 81724
Identification
| Product Name | Proteinase K |
| EC Number | 3.4.21.14 |
| IUPAC Name | (4-nitrophenyl)methyl (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3,4-diphenoxy-5-phosphonooxy-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate |
| Molecular Structure |  |
| CAS Registry Number | 39450-01-6 |
| EINECS Number | 254-457-8 |
| MDL Number | MFCD00132129 |
| Synonyms | (4-nitrophenyl)methyl (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3,4-diphenoxy-5-phosphonooxy-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate AKOS032949645; (4-nitrophenyl)methyl (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3,4-diphenoxy-5-phosphonooxy-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate; (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3,4-diphenoxy-5-phosphonooxy-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (4-nitrophenyl)methyl ester; (4-nitrophenyl)methyl (4R,5S,6S)-4-methyl-6-[(1R)-1-oxidanylethyl]-7-oxidanylidene-3,4-diphenoxy-5-phosphonooxy-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate; (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-7-keto-4-methyl-3,4-diphenoxy-5-phosphonooxy-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (4-nitrobenzyl) ester |
| Molecular Formula | C22H25N5O2 |
| Molecular Weight | 391.466 |
| InChI | InChI=1S/C29H27N2O12P/c1-18(32)23-26(33)30-24(27(34)40-17-19-13-15-20(16-14-19)31(35)36)25(41-21-9-5-3-6-10-21)28(2,29(23,30)43-44(37,38)39)42-22-11-7-4-8-12-22/h3-16,18,23,32H,17H2,1-2H3,(H2,37,38,39)/t18-,23-,28-,29+/m1/s1 |
| InChI Key | OUPAKHMWUJJXOM-ANOMEZDXSA-N |
| Canonical SMILES | CC(C1C(=O)N2C1(C(C(=C2C(=O)OCC3=CC=C(C=C3)[N+](=O)[O-])OC4=CC=CC=C4)(C)OC5=CC=CC=C5)OP(=O)(O)O)O |
| Patent Information |
| No data available |
Physical Data
| Appearance | White or off white, or yellowish powder |
| Solubility | Miscible with water. |
Spectra
| No data available |
Route of Synthesis (ROS)
| No data available |
Safety and Hazards
| Pictogram(s) |   |
| Signal | Danger |
| GHS Hazard Statements | H315 (99.45%): Causes skin irritation [Warning Skin corrosion/irritation] H317 (24.31%): May cause an allergic skin reaction [Warning Sensitization, Skin] H319 (99.45%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H334 (99.45%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory] H335 (32.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. |
| Precautionary Statement Codes | P261, P264, P271, P272, P280, P285, P302+P352, P304+P340, P304+P341, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) For more detailed information, please visit ECHA C&L website |
Source: European Chemicals Agency (ECHA)
License Note: Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: “Source: European Chemicals Agency, http://echa.europa.eu/”. Such acknowledgement must be included in each copy of the material. ECHA permits and encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made to webpages that provide a link to the Legal Notice page.
License URL: https://echa.europa.eu/web/guest/legal-notice
Record Name: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate
URL: https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/213446
Description: The information provided here is aggregated from the “Notified classification and labelling” from ECHA’s C&L Inventory. Read more: https://echa.europa.eu/information-on-chemicals/cl-inventory-database
Other Data
| Transportation | NONH for all modes of transport |
| It is stable by blue ice insulation transport. | |
| HS Code | 350790 |
| Storage | Store lyophilized at -20°C. |
| Market Price | USD |
| Use Pattern |
| Proteinase K EC#: 3.4.21.14 CAS#: 39450-01-6 is a serine protease that displays the ability to digest native proteins, thereby inactivating enzymes such as DNase and RNase without recourse to a denaturation process. |
| Proteinase K EC#: 3.4.21.14 CAS#: 39450-01-6 retains its activity in presence of SDS and urea. It is inactivated by diisopropyl fluorophosphates (DFP) and phenyl methane sulfonyl fluoride (PMSF). |
Related Chemicals
Trypsin inhibitor CAS#: 9035-81-8
Aprotinin CAS#: 9087-70-1
Trypsin EC#: 3.4.21.4 CAS#: 9002-07-7
Protein A CAS#: 91932-65-9
Recombinant Lysyl Endonuclease EC#: 3.4.21.50
Carboxypeptidase B EC#: 3.4.17.2 CAS#: 9025-24-5
Enterokinase EC#: 3.4.21.9 CAS#: 9017-74-8
Recombinant Kex2 Protease EC# 3.4.21.61
Chymotrypsin CAS#: 9004-07-3
Recombinant V8 protease EC#: 3.4.21.19 CAS#: 66676-43-5
Recombinant Protein G
Buy Reagent | |
| No reagent supplier? | Send quick inquiry to ChemWhat |
| Want to be listed here as a reagent supplier? (Paid service) | Click here to contact ChemWhat |
Approved Manufacturers | |
| Watson Bio Ltd | https://www.watson-bio.com/ |
| Want to be listed as an approved manufacturer (Requires approvement)? | Please download and fill out this form and send back to [email protected] |
Contact Us for Other Help | |
| Contact us for other information or services | Click here to contact ChemWhat |