protoasukamycin 4-monooxygenase EC#: 1.14.13.215; ChemWhat Code: 1375457
Product Name | protoasukamycin 4-monooxygenase |
Example Structure | |
Synonyms | asuE1, flavin-dependent protoasukamycin hydroxylase, protoasukamycin 4-hydroxylase |
EC Number | 1.14.13.215 |
CAS Registry Number | |
Comments | The enzyme, characterized from the bacterium Streptomyces nodosus subsp. asukaensis, is involved in the biosynthesis of the antibiotic asukamycin. Requires a flavin cofactor, with no preference among FMN, FAD or riboflavin. When flavin concentration is low, activity is enhanced by the presence of the NADH-dependent flavin-reductase AsuE2. |
Cofactor | flavin |
History | |
Reactions | Protoasukamycin + Nadh + O(2) = 4-hydroxyprotoasukamycin + NAD(+) + H(2)O. |
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