| Product Name |
pterocarpan synthase |
| Example Structure |
 |
| Synonyms |
2′,7-dihydroxy-4′-methoxyisoflavanol dehydratase, 7,2′-dihydroxy-4′-methoxyisoflavanol dehydratase, 7,2-dihydroxy-4-methoxyisoflavanol dehydratase, DMI dehydratase, DMID, medicarpan synthase, medicarpin synthase |
| EC Number |
4.2.1.139 |
| CAS Registry Number |
|
| Comments |
The enzyme catalyses the formation of the additional ring in pterocarpan, the basic structure of phytoalexins produced by leguminous plants, including (?)-medicarpin, (+)-medicarpin, (?)-maackiain and (+)-maackiain. The enzyme requires that the hydroxyl group at C-4 of the substrate is in the (4R) configuration. The configuration of the hydrogen atom at C-3 determines whether the pterocarpan is the (+)- or (?)-enantiomer. The enzyme contains amino acid motifs characteristic of dirigent proteins. Formerly EC?1.1.1.246. |
| Cofactor |
|
| History |
|
| Reactions |
4′-methoxyisoflavan-2′,4,7-triol = (-)-medicarpin + H(2)O. |
