pyrimidine-deoxynucleoside 2′-dioxygenase EC#: 1.14.11.3; ChemWhat Code: 1375074
| Product Name | pyrimidine-deoxynucleoside 2′-dioxygenase |
| Example Structure |  |
| Synonyms | deoxyuridine 2′-dioxygenase, deoxyuridine 2′-hydroxylase, JBP1, JBP2, pyrimidine deoxyribonucleoside 2′-hydroxylase, thymidine 2′-dioxygenase, thymidine 2′-hydroxylase, thymidine 2-oxoglutarate dioxygenase, thymidine dioxygenase |
| EC Number | 1.14.11.3 |
| CAS Registry Number | 9076-89-5 |
| Comments | Requires Fe(II) and ascorbate. Also acts on thymidine. cf. EC 1.14.11.10, pyrimidine-deoxynucleoside 1′-dioxygenase. |
| Cofactor | Fe2+;L-ascorbate |
| History | |
| Reactions | 2′-deoxyuridine + 2-oxoglutarate + O(2) = uridine + succinate + CO(2). |
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