pyrimidodiazepine synthase EC#: 1.5.4.1; ChemWhat Code: 1374465
| Product Name | pyrimidodiazepine synthase |
| Example Structure |  |
| Synonyms | More, PDA synthase |
| EC Number | 1.5.4.1 |
| CAS Registry Number | 93586-06-2 |
| Comments | In the reverse direction of reaction, the reduction of 6-pyruvoyl-tetrahydropterin is accompanied by the opening of the 6-membered pyrazine ring and the formation of the 7-membered diazepine ring. The pyrimidodiazepine involved is an acetyldihydro derivative. Involved in the formation of the eye pigment drosopterin in Drosophila melanogaster. |
| Cofactor | |
| History | |
| Reactions | 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido(4,5-b)[1,4]diazepin-4-one + glutathione disulfide + H(2)O = 6-pyruvoyltetrahydropterin + 2 glutathione. |
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