pyruvate dehydrogenase (quinone) EC#: 1.2.5.1; ChemWhat Code: 1373898
| Product Name | pyruvate dehydrogenase (quinone) |
| Example Structure |  |
| Synonyms | EC 1.2.2.2, ECPOX, POX, poxB, POXEC, pqo, pyruvate (quinone) dehydrogenase, pyruvate oxidase, pyruvate oxidase B, pyruvate:quinone oxidoreductase, pyruvate:ubiquinone-8-oxidoreductase, ubiquinione-dependent pyruvate oxidase, ubiquinone-dependent pyruvate oxidase |
| EC Number | 1.2.5.1 |
| CAS Registry Number | |
| Comments | Flavoprotein (FAD) [1]. This bacterial enzyme is located on the inner surface of the cytoplasmic membrane and coupled to the respiratory chain via ubiquinone [2,3]. Does not accept menaquinone. Activity is greatly enhanced by lipids [4,5,6]. Requires thiamine diphosphate [7]. The enzyme can also form acetoin [8]. |
| Cofactor | FAD |
| History | |
| Reactions | Pyruvate + ubiquinone + H(2)O = acetate + CO(2) + ubiquinol. |
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