| Product Name |
(R)-2-hydroxy-4-methylpentanoate CoA-transferase |
| Example Structure |
 |
| Synonyms |
(R)-2-hydroxyisocaproate CoA transferase, HadA |
| EC Number |
2.8.3.24 |
| CAS Registry Number |
|
| Comments |
The enzyme, characterized from the bacterium?Peptoclostridium difficile, participates in an?L-leucine fermentation pathway. The reaction proceeds via formation of a covalent anhydride intermediate between a conserved aspartate residue and the acyl group of the CoA thioester substrate. |
| Cofactor |
|
| History |
|
| Reactions |
4-methylpentanoyl-CoA + (R)-2-hydroxy-4-methylpentanoate = 4-methylpentanoate + (R)-2-hydroxy-4-methylpentanoyl-CoA. |
