| Product Name |
(R)-2-hydroxyisocaproyl-CoA dehydratase |
| Example Structure |
 |
| Synonyms |
2-hydroxyisocaproyl-CoA dehydratase, HadBC, HadBC dehydratase |
| EC Number |
4.2.1.157 |
| CAS Registry Number |
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| Comments |
The enzyme, isolated from the bacterium?Peptoclostridium difficile, is involved in the reductive branch of?L-leucine fermentation. It catalyses an ¦Á/¦Â-dehydration, which depends on the reductive formation of ketyl radicals on the substrate generated by injection of a single electron from the ATP-dependent activator protein HadI. |
| Cofactor |
|
| History |
|
| Reactions |
(R)-2-hydroxy-4-methylpentanoyl-CoA = 4-methylpent-2-enoyl-CoA + H(2)O. |
