(R)-6-hydroxynicotine oxidase EC#: 1.5.3.6; ChemWhat Code: 1374441
| Product Name | (R)-6-hydroxynicotine oxidase |
| Example Structure |  |
| Synonyms | 6-HDNO, 6-hydroxy-D-nicotine oxidase, D-6-hydroxynicotine oxidase |
| EC Number | 1.5.3.6 |
| CAS Registry Number | 37233-46-8 |
| Comments | A flavoprotein (FAD). The enzyme, which participates in nicotine degradation, is specific for (R) isomer of 6-hydroxynicotine, derived from the uncommon (R)-nicotine. The bacterium Arthrobacter nicotinovorans, in which this enzyme was originally discovered, has a different enzyme that catalyses a similar reaction with the (S)-isomer (cf. EC 1.5.3.5, (S)-6-hydroxynicotine oxidase). |
| Cofactor | FAD |
| History | |
| Reactions | (R)-6-hydroxynicotine + H(2)O + O(2) = 1-(6-hydroxypyridin-3-yl)-4- (methylamino)butan-1-one + H(2)O(2). |
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