(R)-benzylsuccinyl-CoA dehydrogenase EC#: 1.3.8.3; ChemWhat Code: 1374160
| Product Name | (R)-benzylsuccinyl-CoA dehydrogenase |
| Example Structure |  |
| Synonyms | BbsG |
| EC Number | 1.3.8.3 |
| CAS Registry Number | |
| Comments | Requires FAD as prosthetic group. Unlike other acyl-CoA dehydrogenases, this enzyme exhibits high substrate- and enantiomer specificity it is highly specific for (R)-benzylsuccinyl-CoA and is inhibited by (S)-benzylsuccinyl-CoA. Forms the third step in the anaerobic toluene metabolic pathway in Thauera aromatica. Ferricenium ion is an effective artificial electron acceptor. |
| Cofactor | FAD |
| History | |
| Reactions | (R)-2-benzylsuccinyl-CoA + electron-transfer flavoprotein = (E)-2- benzylidenesuccinyl-CoA + reduced electron-transfer flavoprotein. |
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