(R)-pantolactone dehydrogenase (flavin) EC#: 1.1.99.27; ChemWhat Code: 1373701

Product Name (R)-pantolactone dehydrogenase (flavin)
Example Structure Example Structure of (R)-pantolactone dehydrogenase (flavin) EC#: 1.1.99.27
Synonyms (R)-Pantoyllactone dehydrogenase (flavin), 2-Dehydropantolactone reductase (flavin), 2-Dehydropantoyl-lactone reductase (flavin), dehydrogenase, L-(+)-pantoyllactone
EC Number 1.1.99.27
CAS Registry Number 140879-14-7
Comments high specificity for (R)-pantolactone. Phenazine methosulfate (PMS) can act as acceptor. The enzyme has been studied in the bacterium Nocardia asteroides and shown to be membrane-bound and induced by 1,2-propanediol. The FMN cofactor is non-covalently bound.
Cofactor FMN
History
Reactions (R)-pantolactone + acceptor = 2-dehydropantolactone + reduced acceptor.

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