Troponin T is one of three troponin isoforms found in the tropomyosin-troponin complex. This complex is responsible for the calcium sensitivity of the contractile apparatus in the muscle. Cardiac Troponin T is used as a biological marker for cardiomyocytes and its level in serum is frequently used as an indicator of myocardial cell injury.
Source
Molecular Weight
Approximately 35.8 kDa, a single non-glycosylated polypeptide chain containing 297 amino acids.
Biological Activity
No data available.
Appearance
Sterile colorless liquid.
Formulation
Supplied as a 0.2 um filtered solution in 10 mM Tris-HCl, pH8.0, 250 mM NaCl, with 50% glycerol.
Endotoxin
Less than 1 EU/ug of rHucTnT as determined by LAL method.
Reconstitution
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 6 months from date of receipt, -20 to -70 °C as supplied.- 3 months, -20 to -70 °C under sterile conditions after opening.
