retinoid isomerohydrolase EC#: 3.1.1.64; ChemWhat Code: 1379270
| Product Name | retinoid isomerohydrolase |
| Example Structure |  |
| Synonyms | 13-cis isomerohydrolase, 13cIMH, all-trans-REH, all-trans-retinyl-palmitate hydrolase, esterase, all-trans-retinol palmitate, IMH, isomerohydrolase, Retinoid isomerase, retinoid isomerohydrolase, retinol hydrolase (ambiguous), retinol isomerase-2, retinol isomerohydrolase, RPE isomerase, Rpe65, RPE65a, RPE65c |
| EC Number | 3.1.1.64 |
| CAS Registry Number | |
| Comments | This enzyme, which operates in the retinal pigment epithelium (RPE), catalyses the cleavage and isomerization of?all-trans-retinyl fatty acid esters to 11-cis-retinol, a key step in the regeneration of the visual chromophore in the vertebrate visual cycle [4]. Interaction of the enzyme with the membrane is critical for its enzymatic activity [6]. |
| Cofactor | |
| History | |
| Reactions | An all-trans-retinyl ester + H(2)O = 11-cis-retinol + a fatty acid. |
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