ruberlysin EC#: 3.4.24.48; ChemWhat Code: 1381038

Product Name ruberlysin
Example Structure Example Structure of ruberlysin EC#: 3.4.24.48
Synonyms Crotalus ruber metalloendopeptidase II, Hemorrhagic toxin II, HT-2, red rattlesnake metalloendopeptidase
EC Number 3.4.24.48
CAS Registry Number 81669-70-7
Comments A 25 kDa hemorrhagic endopeptidase from the venom of the red rattlesnake (Crotalus ruber ruber) that cleaves fibrinogen. In peptidase family?M12?(astacin family).
Cofactor Zn2+
History
Reactions Cleavage of 10-His-|-Leu-11, 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17 and 23-Gly-|-Phe-24 bonds of the B chain of insulin; His-|-Pro, Pro-|-Phe, and Trp-|-Ser of angiotensin I; and Gly-|-Phe of Met enkephalin.

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