russellysin EC#: 3.4.24.58; ChemWhat Code: 1381052

Product Name russellysin
Example Structure Example Structure of russellysin EC#: 3.4.24.58
Synonyms Blood-coagulation factor X activating enzyme, EC 3.4.21.23, Metalloproteinase RVV-x, Proteinase, Vipera russelli, Russell’s viper blood coagulation factor X activator, Russell’s viper venom factor X activator, RVV-X, Russell`s viper venom coagulation factor X-activating enzyme, Russell¡¯s viper venom factor X activator, RVV-V, RVV-X, snake venom protease
EC Number 3.4.24.58
CAS Registry Number 79393-92-3
Comments This enzyme from the venom of Russell’s viper (Vipera russelli) of 79 kDa comprises a heavy (59 kDa) and a heterogeneous light (18-21 kDa) chain. Contains Ca2+?and Zn2+. The heavy chain contains the zinc-binding endopeptidase domain and a disintegrin. In peptidase family M12 (astacin family).
Cofactor Zn2+;Ca2+
History
Reactions Specifically activates several components of the blood clotting system, including coagulation factor X, coagulation factor ix and protein c by cleavage of Arg-|-Xaa bonds. Has no action on insulin B chain.

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