(S)-norcoclaurine synthase EC#: 4.2.1.78; ChemWhat Code: 1382354
Product Name | (S)-norcoclaurine synthase |
Example Structure | |
Synonyms | (S)-norcoclaurine synthase, (S)-Norlaudanosoline synthase, AmNCS1, AmNCS2, CCHNCS2, CjNCS1, CjPR10A, CsNCS, More, NCS, NCS1, NCS2, NDONCS3, norcoclaurine synthase, PbNCS, PR10A, PSONCS1, PSONCS2, S-norcoclaurine synthase, Synthase, (S)-norlaudanosoline, TFLNCSDELTA25, TfNCS |
EC Number | 4.2.1.78 |
CAS Registry Number | 79122-01-3 |
Comments | The reaction makes a six-membered ring by forming a bond between C-6 of the 3,4-dihydroxyphenyl group of the dopamine and C-1 of the aldehyde in the imine formed between the substrates. The product is the precursor of the benzylisoquinoline alkaloids in plants. The enzyme, formerly known as (S)-norlaudanosoline synthase, will also catalyse the reaction of 4-(2-aminoethyl)benzene-1,2-diol + (3,4-dihydroxyphenyl)acetaldehyde to form (S)-norlaudanosoline, but this alkaloid has not been found to occur in plants. |
Cofactor | |
History | |
Reactions | Dopamine + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H(2)O. |
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