Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

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Identification

Product Name	(S)-Pro-xylane
IUPAC Name
Molecular Structure
CAS Registry Number	868156-46-1
EINECS Number
MDL Number	MFCD32701904
Beilstein Registry Number
Synonyms
Molecular Formula	C8H16O5
Molecular Weight	192.210
InChI
InChI Key
Canonical SMILES

Patent Information
Patent ID	Title	Publication Date
US2005/250708	Novel C-glycosides, uses thereof	2005

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Physical Data

Appearance

Solid

Melting Point, °C

120 – 122

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Spectra

Description (NMR Spectroscopy)	Nucleus (NMR Spectroscopy)	Solvents (NMR Spectroscopy)
Chemical shifts, Spectrum	1H	water-d2
Chemical shifts, Spectrum	13C	water-d2
Chemical shifts	1H
Chemical shifts	13C
Chemical shifts	1H	CD3OD

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Route of Synthesis (ROS)

Conditions	Yield
With sodium tris(acetoxy)borohydride In isopropyl alcohol at 20℃; Product distribution / selectivity; Experimental Procedure 2 Production of C-β-D-xylopyranoside-2-(S)-hydroxypropane EXAMPLE 2 Production of C-β-D-xylopyranoside-2-(S)-hydroxypropane The expected compound was obtained according the process described in Example 1, replacing the 2 ml of acetic acid and the sodium borohydride with two times 1.2 equivalents of sodium triacetoxyborohydride (NaBH(OAc)3). The product was obtained with a quantitative yield, and selectively in (β, S) form. The physico chemical characteristics are identical in all respects to those obtained in Example 1.	100%
With sodium tetrahydroborate; acetic acid In isopropyl alcohol at 20℃; for 1.5h; Product distribution / selectivity; Experimental Procedure 1 Production of C-β-D-xylopyranoside-2-(S)-hydroxypropane EXAMPLE 1 Production of C-β-D-xylopyranoside-2-(S)-hydroxypropane 2 ml of acetic acid, followed rapidly by 120 mg (1.2 eq.) of sodium borohydride as granules were added to a solution of 500 mg of C-β-D-xylopyranoside-2-propanone (described in Example 1 of application WO-02/051828) in 9 ml of isopropanol. The medium was left at ambient temperature for 30 minutes with stirring. 120 mg (1.2 eq.) of sodium borohydride as granules were then added. The reaction medium was left for 1 hour at ambient temperature with stirring. 10 ml of acetone were then added and, after stirring for 30 minutes at ambient temperature, the reaction medium was concentrated under vacuum. The residue obtained was purified by silica gel chromatography so as to selectively produce the expected compound C-β-D-xylopyranoside-2-(S)-hydroxypropane with a 95% yield. Physico chemical characteristics of the compound: Melting point: 120-122° C. Optical rotation: -37° (at 20° C. in methanol, and at a concentration [C]=1 g/100 ml) 1H NMR: 1.03 (t, 3H); 1.46 (m, 1H); 1.71 (m, 1H); 2.85 (m, 1H); 2.94 (m, 1H); 2.99 (m, 2H); 3.24 (m, 1H); 3.67 (m, 1H); 3.77 (m, 1H) Structure confirmed by X-ray diffraction.	95%

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Safety and Hazards

Pictogram(s)
Signal
GHS Hazard Statements	Not Classified
Precautionary Statement Codes

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Other Data

Druglikeness
Lipinski rules component
Molecular Weight	192.212
logP	-1.202
HBA	5
HBD	4
Matching Lipinski Rules	4
Veber rules component
Polar Surface Area (PSA)	90.15
Rotatable Bond (RotB)	2
Matching Veber Rules	2

Use Pattern

Anti-aging, promotes skin cell renewal, helps repair and rebuild the skin’s collagen and glycosaminoglycans, thereby reducing wrinkles and fine lines. Moisturizing and nourishing, promotes the synthesis of collagen, repairs damaged skin; enhances overall skin health.

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