SARS coronavirus main proteinase EC#: 3.4.22.69; ChemWhat Code: 1380817

Product Name SARS coronavirus main proteinase
Example Structure Example Structure of SARS coronavirus main proteinase EC#: 3.4.22.69
Synonyms 3C-like protease, 3CL protease, 3cLpro, C30.004, chymotrypsin-like protease, coronavirus 3C-like protease, coronavirus M(pro), coronavirus main protease, main protease, Mpro, porcine transmissible gastroenteritis virus Mpro, SARS 3C-like protease, SARS 3C-like proteinase, SARS 3CL protease, SARS 3CLpro, SARS coronavirus 3C-like protease, SARS coronavirus 3C-like proteinase, SARS coronavirus 3CL protease, SARS coronavirus main peptidase, SARS coronavirus main protease, SARS coronavirus main proteinase, SARS coronavirus Mpro, SARS CoV main proteinase, SARS CoVMpro, SARS main protease, SARS Mpro, SARS-3CL protease, SARS-3CLpro, SARS-coronavirus 3CL protease, SARS-coronavirus main protease, SARS-CoV 3C-like peptidase, SARS-CoV 3C-like protease, SARS-CoV 3CL peptidase, SARS-CoV 3CL protease, SARS-CoV 3CLpro, SARS-CoV 3CLpro enzyme, SARS-CoV 3CLpro protease, SARS-CoV main protease, SARS-CoV Mpro, SARSCoV main protease, SARSCoV Mpro, severe acute respiratory syndrome coronavirus 3C-like protease, severe acute respiratory syndrome coronavirus 3CLpro, severe acute respiratory syndrome coronavirus main protease, severe acute respiratory syndrome coronavirus main proteinase, severe acute respiratory syndrome coronavirus Mpro, TGEV Mpro
EC Number 3.4.22.69
CAS Registry Number
Comments SARS coronavirus main protease is the key enzyme in SARS coronavirus replicase polyprotein processing. In peptidase family?C30.
Cofactor
History
Reactions Tsavlq-|-SGFRK-NH(2) and sgvtfq-|-gkfkk the two peptides corresponding to the two self-cleavage sites of the Sars 3C-like proteinase are the two most reactive peptide substrates. The enzyme exhibits a strong preference for substrates containing Gln at P1 position and Leu at P2 position.

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