Signal peptidase II EC#: 3.4.23.36; ChemWhat Code: 1380903
| Product Name | Signal peptidase II |
| Example Structure |  |
| Synonyms | EC 3.4.99.35, Leader peptidase II, lipoprotein signal peptidase, lipoprotein signal peptidase II, lipoprotein-specific (typeII) signal peptidase, lipoprotein-specific signal peptidase, lipoprotein-specific type II signal peptidase, LspA, More, Premurein leader peptidase, Premurein leader proteinase, Premurein-leader peptidase, Prolipoprotein signal peptidase, Proteinase, premurein leader, Sp0928, SPase II, SpiI, type II signal peptidase |
| EC Number | 3.4.23.36 |
| CAS Registry Number | 171715-14-3 |
| Comments | An 18-kDa enzyme present in bacterial inner membranes. Inhibited by pepstatin and the antibiotic globomycin. Type example of peptidase family?A8. Formerly EC?3.4.99.35. |
| Cofactor | |
| History | |
| Reactions | Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains. |
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