spermine oxidase EC#: 1.5.3.16; ChemWhat Code: 1374456

Product Name spermine oxidase
Example Structure Example Structure of spermine oxidase EC#: 1.5.3.16
Synonyms AtPAO1, AtPAO4, AtPAO5, Fms1 protein, GhPAO, hSMO, MmSMO, mSMO, mSMOalpha, mSMOmu, PAO, PAO1, PAO4, PAOh1, PAOh1/SMO, SelPAO5, SMO, SMO(PAOh1), SMO/PAOh1, SMO5, SMOX, spermine oxidase, Spm oxidase, thermospermine oxidase
EC Number 1.5.3.16
CAS Registry Number
Comments The enzyme from Arabidopsis thaliana (AtPAO1) oxidizes norspermine to norspermidine with high efficiency [3]. The mammalian enzyme, encoded by the SMOX gene, is a cytosolic enzyme that catalyses the oxidation of spermine at the exo (three-carbon) side of the tertiary amine. No activity with spermidine. Weak activity with N1-acetylspermine. A flavoprotein (FAD). Differs in specificity from EC 1.5.3.13 (N1-acetylpolyamine oxidase), EC 1.5.3.14 (polyamine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.15 (N8-acetylspermidine oxidase (propane-1,3-diamine-forming)) and EC 1.5.3.17 (non-specific polyamine oxidase).
Cofactor FAD
History
Reactions Spermine + O(2) + H(2)O = spermidine + 3-aminopropanal + H(2)O(2).

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