sphingosine kinase EC#: 2.7.1.91; ChemWhat Code: 1378444

Product Name sphingosine kinase
Example Structure Example Structure of sphingosine kinase EC#: 2.7.1.91
Synonyms dihydrosphingosine kinase, kinase, dihydrosphingosine (phosphorylating), kinase, sphingosine (phosphorylating), More, SGK, SK, SK-1, SK-2, SK1, SK2, sphinganine kinase, sphingoid base kinase, sphingosine kinase, sphingosine kinase 1, sphingosine kinase 2, sphingosine kinase type 1, sphingosine kinase type 2, sphingosine kinase-1, sphingosine kinase-2, SPHK, SPHK1, SPHK1a, SPHK1b, SPHK2, SPK
EC Number 2.7.1.91
CAS Registry Number 50864-48-7
Comments The enzyme is involved in the production of sphingolipid metabolites. It phosphorylates various sphingoid long-chain bases, such as sphingosine,?D-erythro-dihydrosphingosine (sphinganine), phytosphingosine (4-hydroxysphinganine), 4-hydroxy-8-sphingenine, 4,8-sphingadienine and?D-threo-dihydrosphingosine and?L-threo-dihydrosphingosine. The exact substrate range depends on the species.
Cofactor
History
Reactions Atp + a sphingoid base = adp + a sphingoid base 1-phosphate.

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