squalene monooxygenase EC#: 1.14.14.17; ChemWhat Code: 1375519
| Product Name | squalene monooxygenase |
| Example Structure |  |
| Synonyms | CYP17, cytochrome P450 17alpha hydroxylase/17,20 lyase, Erg1, Erg1 protein, Erg1p, hydroxylase, squalene, oxygenase, squalene mono-, SE, SE1, SE3, SQE-I, SQE-II, SQE3, SQLE, squalen expoxidase, squalene 2,3-epoxidase, squalene 2,3-oxidocyclase, squalene epoxidase, squalene epoxidase 1, squalene epoxidase 3, squalene hydroxylase, squalene mono-oxygenase, squalene oxydocyclase, squalene-2,3-epoxidase, squalene-2,3-epoxide cyclase |
| EC Number | 1.14.14.17 |
| CAS Registry Number | 9029-62-3 |
| Comments | A flavoprotein (FAD). This enzyme, together with EC 5.4.99.7 lanosterol synthase, was formerly known as squalene oxidocyclase. The electron donor is EC 1.6.2.4, NADPH¡ªhemoprotein reductase [5,7]. |
| Cofactor | FAD |
| History | |
| Reactions | Squalene + [reduced NADPH–hemoprotein reductase] + O(2) = (3S)-2,3- epoxy-2,3-dihydrosqualene + [oxidized NADPH–hemoprotein reductase] + H(2)O. |
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