Ste24 endopeptidase EC#: 3.4.24.84; ChemWhat Code: 1381095
| Product Name | Ste24 endopeptidase |
| Example Structure | ![]() |
| Synonyms | a-factor converting enzyme, Afc1, Afc1p, At Ste24p, AtSte24, CAAX prenyl protease 1 homolog, FACE-1, Hs Ste24p, Sc Ste24p, Ste24p, Zmpste24 |
| EC Number | 3.4.24.84 |
| CAS Registry Number | |
| Comments | Type example of peptidase family?M48. One of two enzymes that can catalyse this processing step for mating a-factor in yeast. Subsequently, the?S-isoprenylated cysteine residue that forms the new C-terminus is methyl-esterified and forms a hydrophobic membrane-anchor. |
| Cofactor | Zn2+ |
| History | |
| Reactions | The peptide bond hydrolyzed can be designated -C-|-A-A-X in which C is an S-isoprenylated cysteine residue, A is usually aliphatic and x is the C-terminal residue of the substrate protein, and may be any of several amino acids. |
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