Ste24 endopeptidase EC#: 3.4.24.84; ChemWhat Code: 1381095

Product Name Ste24 endopeptidase
Example Structure Example Structure of Ste24 endopeptidase EC#: 3.4.24.84
Synonyms a-factor converting enzyme, Afc1, Afc1p, At Ste24p, AtSte24, CAAX prenyl protease 1 homolog, FACE-1, Hs Ste24p, Sc Ste24p, Ste24p, Zmpste24
EC Number 3.4.24.84
CAS Registry Number
Comments Type example of peptidase family?M48. One of two enzymes that can catalyse this processing step for mating a-factor in yeast. Subsequently, the?S-isoprenylated cysteine residue that forms the new C-terminus is methyl-esterified and forms a hydrophobic membrane-anchor.
Cofactor Zn2+
History
Reactions The peptide bond hydrolyzed can be designated -C-|-A-A-X in which C is an S-isoprenylated cysteine residue, A is usually aliphatic and x is the C-terminal residue of the substrate protein, and may be any of several amino acids.

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