steroid 15beta-monooxygenase EC#: 1.14.15.8; ChemWhat Code: 1375692
Product Name | steroid 15beta-monooxygenase |
Example Structure | |
Synonyms | 15beta-hydroxylase, 15beta-hydroxylase CYP106A2, BmCYP106A2, Cyp106A1, CYP106A2, cytochrome P-450meg, cytochrome P450meg, steroid-15-beta-monooxygenase |
EC Number | 1.14.15.8 |
CAS Registry Number | |
Comments | The enzyme from Bacillus megaterium hydroxylates a variety of 3-oxo-¦¤4-steroids in position 15¦Â. Ring A-reduced, aromatic, and 3¦Â-hydroxy-¦¤4-steroids do not serve as substrates [2]. |
Cofactor | |
History | |
Reactions | Progesterone + 2 reduced [2Fe-2S] ferredoxin + O(2) = 15-beta- hydroxyprogesterone + 2 oxidized [2Fe-2S] ferredoxin + H(2)O. |
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