sterol 14alpha-demethylase EC#: 1.14.14.154; ChemWhat Code: 1375662

Product Name sterol 14alpha-demethylase
Example Structure Example Structure of sterol 14alpha-demethylase EC#: 1.14.14.154
Synonyms 14-alpha sterol demethylase, 14-demethylase, 14alpha-demethylase, 14alpha-lanosterol demethylase, 14alpha-methylsterol 14alpha-demethylase, 14alpha-sterol demethylase, 14DM, AF_14DM, C- I4 demethylase, CACYP51, CA_14DM, CYP51, Cyp51A, CYP51A1, CYP51Ap, CYP51B, CYP51b1, CYP51Bp, CYP51F1, CYP51G1, CYPL1, cytochrome CYP51, cytochrome P 450 CYP51, cytochrome P-450 lanosterol 14alpha-demethylase, cytochrome P-450-dependent 14alpha-sterol demethylase, cytochrome P-450-dependent obtusifoliol 14alpha-demethylase, cytochrome P-450/14DM, cytochrome P-45014DM, cytochrome P450 14alpha-demethylase, cytochrome P450 14DM, cytochrome P450 51, cytochrome P450 CYP51, cytochrome P450 lanosterol 14alpha-demethylase, cytochrome P450 sterol 14alpha-demethylase, cytochrome-P450 14alpha-demethylase, demethylase, methylsterol 14alpha-, eburicol 14 alpha-demethylase, eburicol 14alpha-demethylase, ERG11, Erg11p, lanosterol 14 alpha-demethylase, lanosterol 14-alpha demethylase, lanosterol 14-demethylase, lanosterol 14alpha-demethylase, lanosterol 14alpha-methyldemethylase, lanosterol C-14 demethylase, lanosterol demethylase, lanosterol-14alpha-demethylase, LDM, methylsterol 14alpha-demethylase (P 450 CYP51), More, Obtusifoliol 14-alpha demethylase, obtusifoliol 14-demethylase, obtusifoliol 14alpha-demethylase, obtusifoliol-metabolizing 14alpha-demethylase, obtusufoliol 14-demethylase, P 450 lanosterol C-14 demethylase, P-450 lanosterol demethylase, P-45014DM, P-45014DM-containing monooxygenase system, P-450OBT 14DM, P450 14alpha-lanosterol demethylases A, P450 14alpha-lanosterol demethylases B, P450(14DM), P450-14DM, P450-L1A1, P45014DM, PCERG11, rLDM, sterol 14-alpha demethylase, sterol 14-demethylase, sterol 14-demethylase P450, sterol 14alpha-demethylase, sterol 14alpha-demethylase (CYP51), sterol 14alpha-demethylase cytochrome P 450, sterol 14alpha-demethylase P450, sterol C14 demethylase, sterol C14-demethylase, sterol demethylase P450, sterol-14alpha-demethylase, TC14DM
EC Number 1.14.14.154
CAS Registry Number
Comments This cytochrome P450 (heme-thiolate) enzyme acts on a range of steroids with a 14¦Á-methyl group, such as obtusifoliol and lanosterol. The enzyme catalyses a hydroxylation and a reduction of the 14¦Á-methyl group, followed by a second hydroxylation, resulting in the elimination of formate and formation of a 14(15) double bond. Formerly EC 1.14.13.70.
Cofactor heme-thiolate
History
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