Subtilisin EC#: 3.4.21.62; ChemWhat Code: 1380571

Product Name Subtilisin
Example Structure Example Structure of Subtilisin EC#: 3.4.21.62
Synonyms AcpII, Ak.1 protease, Alcalase, Alcalase 0.6L, Alcalase 2.5L, ALE1 subtilase, ALK-enzyme, Alkaline mesentericopeptidase, Alkaline protease, ALP1, Alzwiprase, AprE51, aqualysin, Arp, AsES, Asp v 13, Bacillopeptidase A, Bacillopeptidase B, Bacillus gibsonii alkaline protease, Bacillus subtilis alkaline proteinase Bioprase, BgAP, Bioprase AL 15, Bioprase APL 30, BLS, BPN’, BprB, BprV, C1 subtilase, Colistinase, EC 3.4.21.14, EC 3.4.4.16, Esperase, Fe protease, Genenase I, intracellular subtilisin protease, ISP, Kazusase, Maxatase, mesenteroicopeptidase, More, Nagarse, Opticlean, Orientase 10B, P69 subtilase, Peptidase, subtilo-, A, phytophase, Protease S, Protease VIII, Protease XXVII, Proteinase K, Proteinase, Bacillus subtilis alkaline, Protin A 3L, PSP-3, psychrophilic subtilisin-like protease, S1P subtilase, SAS-1, SASP, saspase, Savinase, Savinase 16.0L, Savinase 32.0 L EX, Savinase 4.0T, Savinase 8.0L, savinaseTM, SBc, SBL, SDD1 subtilase, senescence-associated subtilisin protease, SISBT3 subtilase, SP 266, Sspa, SSU0757, SUB1, SUB2, subtilisin, subtilisin 72, subtilisin A, Subtilisin amylosacchariticus, Subtilisin BL, subtilisin BPN¡¯, subtilisin C., subtilisin Carlsberg, subtilisin DJ-4, Subtilisin DY, Subtilisin E, Subtilisin GX, subtilisin JB1, subtilisin Karlsberg, Subtilisin Novo, subtilisin Pr1-like protease, subtilisin protease, subtilisin QK, Subtilisin S41, subtilisin S4I, subtilisin S88, Subtilisin Sendai, subtilisin Sph, subtilisin-like protease, subtilisin-like protease AprV2, subtilisin-like serine protease, Subtilisn J, Subtilopeptidase, Superase, thermitase, Thermoase, Thermoase PC 10, thermophilic thermitase, thermostable subtilisin, ThSS45, Tk-subtilisin, trans-cinnamoyl-subtilisin
EC Number 3.4.21.62
CAS Registry Number 9014/1/1
Comments Subtilisin is a serine endopeptidase, type example of peptidase family?S8. It contains no cysteine residues (although these are found in homologous enzymes). Species variants include subtilisin BPN’ (also subtilisin B, subtilopeptidase B, subtilopeptidase C, Nagarse, Nagarse proteinase, subtilisin Novo, bacterial proteinase Novo) and subtilisin Carlsberg (subtilisin A, subtilopeptidase A, alcalase Novo). Formerly EC?3.4.4.16?and included in EC?3.4.21.14. Similar enzymes are produced by various?Bacillus subtilis?strains and other?Bacillus?species [1, 3].
Cofactor
History
Reactions Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.

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