succinate-semialdehyde dehydrogenase (acylating) EC#: 1.2.1.76; ChemWhat Code: 1373836
| Product Name | succinate-semialdehyde dehydrogenase (acylating) |
| Example Structure |  |
| Synonyms | Tneu_0421 |
| EC Number | 1.2.1.76 |
| CAS Registry Number | |
| Comments | Catalyses the NADPH-dependent reduction of succinyl-CoA to succinate semialdehyde. The enzyme has been described in Clostridium kluyveri, where it participates in succinate fermentation [1], and in Metallosphaera sedula, where it participates in the 3-hydroxypropionate/4-hydroxybutyrate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea [2,3]. |
| Cofactor | |
| History | |
| Reactions | Succinate semialdehyde + CoA + NADP(+) = succinyl-CoA + Nadph. |
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