succinylglutamate desuccinylase EC#: 3.5.1.96; ChemWhat Code: 1381300
| Product Name | succinylglutamate desuccinylase |
| Example Structure |  |
| Synonyms | aruE |
| EC Number | 3.5.1.96 |
| CAS Registry Number | |
| Comments | Requires Co2+?for maximal activity [1].?N2-Acetylglutamate is not a substrate. This is the final enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine [1]. This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. The five enzymes involved in this pathway are EC?2.3.1.109?(arginine?N-succinyltransferase), EC?3.5.3.23?(N-succinylarginine dihydrolase), EC?2.6.1.11?(acetylornithine transaminase), EC?1.2.1.71?(succinylglutamate-semialdehyde dehydrogenase) and EC?3.5.1.96?(succinylglutamate desuccinylase). |
| Cofactor | cobalt cation |
| History | |
| Reactions | N-succinyl-L-glutamate + H(2)O = succinate + L-glutamate. |
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